| ncRNA name | AFAP1-AS1 |
| ncRNA Category | lncRNA |
| ID | 84740 |
| Ensembl | ENSG00000272620 |
| Synonyms | AFAP1AS; AFAP1-AS |
| Disease name | retinoblastoma (RB) |
| Species | Homo sapiens |
| Tissues/Cell_line | RB samples, normal retinas; RB cell lines Y79 and WERI-RB1; RPE cell line ARPE-19; human retinal microvascular endothelial cells (HRMECs) |
| Methods | qPCR, transfection, CCK-8 assay, transwell assay |
| Expression pattern | up-regulated |
| Functional description | AFAP1-AS1 expression was elevated in retinoblastoma tissues and cell lines, and associated with tumor size, choroidal invasion, and optic nerve invasion. Moreover, high expression of AFAP1-AS1 was an independent unfavorable prognostic factor in retinoblastoma patients. |
| PubMed ID | 29654169 |
| Year | 2018 |
| Title | LncRNA AFAP1-AS1 is a prognostic biomarker and serves as oncogenic role in retinoblastoma. |
| Drug-related ncRNA | NO |
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